Benzyl Bromide → HCID 13091191, compound

Participants

Reaction Steps

A mixture of ethyl 5-(3,4-dihydroxyphenyl)-4-oxo-4H-pyran-2-carboxylate (3.0 g), anhydrous potassium carbonate (6.0 g) and benzyl bromide (3.0 ml) in dry DMF (30 ml) was stirred at room temperature for 2 hours and then filtered. The filtrate was cooled, acidified with 2 N hydrochloric acid (20 ml) and diluted with water (80 ml). The solid product was recrystallised from ethanol to give ethyl 5-(3,4-dibenzyloxyphenyl)-4-oxo-4H-pyran-2-carboxylate (mp 122°-125° C.).

Provenance & Evidence