HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1902796Generated: November 2, 2026
Ammonia → 2-[(aminocarbamothioyl)amino]acetamide
https://huagongshe.com/reaction/1902796
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Ammonia | HCID 222 | — |
| Reactant | Ethyl N-(hydrazinecarbothioyl)glycinate | HCID 3810781 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 2-[(aminocarbamothioyl)amino]acetamide | HCID 20514820 | — |
Reaction Steps
4-Ethoxycarbonylmethyl-thiosemicarbazide (8.33 g) (GANTE and LANTSCH, Chem. Ber., 97, 989 (1964)) are suspended in a saturated solution (250 cc) of ammonia in ethanol, and the reaction mixture is stirred at 25° C. for 22 hours. The insoluble matter is filtered off and washed with alcohol (2×25 cc) and ether (2×50 cc); after drying, 4-carbamylmethyl-thiosemicarbazide (6.2 g), m.p.=188° C., is obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US04365062 |
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| Source dataset | uspto-grants-1982_12 |
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| ORD ID | ord-45c9183759fd4db5be3f7083c1469e91 |
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| Source note | uspto-grants-1982_12 |
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