HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,3-Propanediamine → N,N"-1,3-Propanediylbis-[N'-[3-[3-[(dimethylamino) methyl]phenoxy]propyl]thiourea]
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,3-Propanediamine | HCID 428 | — |
| Reactant | HCID 20513976 | HCID 20513976 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | N,N"-1,3-Propanediylbis-[N'-[3-[3-[(dimethylamino) methyl]phenoxy]propyl]thiourea] | HCID 20549772 | 17.9% |
Reaction Steps
A mixture of 3-(3-isothiocyanatopropoxy)-N,N-dimethylbenzenemethanamine (2.24 g) and 1,3-diaminopropane (0.42 g) in acetonitrile (50 ml) was stirred at room temperature for 24 hours. The solvent was evaporated in vacuo and the oily residue chromatographed (silica/methanol) to yield the title compound (0.46 g) as a gum.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04366164 |
| Source dataset | uspto-grants-1982_12 |
| ORD ID | ord-5737217953364548aa269a844b9e81de |
| Source note | uspto-grants-1982_12 |