HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Bicarbonate → 1-Methylthio-1-[3-[3-(piperidinomethyl)phenoxy]propyl]amino-2-nitroethene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Bicarbonate | HCID 516892 | — |
| Reactant | 2-Nitro-N-[3-[3-(1-piperidinylmethyl)phenoxy]propyl]-1-(methylthio)etheneamine oxalate | HCID 70547227 | — |
| Solvent | Water | HCID 962 | — |
| Product | 1-Methylthio-1-[3-[3-(piperidinomethyl)phenoxy]propyl]amino-2-nitroethene | HCID 67882093 | 90% |
Reaction Steps
To a solution of 2-nitro-N-[3-[3-(1-piperidinylmethyl)phenoxy]propyl]-1-(methylthio)ethenamine oxalate (0.9 g.) in water (20 ml.) was added sodium bicarbonate (3 g.). The suspension was extracted with ethyl acetate (2×20 ml.), the extracts dried (Na2CO3) and evaporated in vacuo to give the title compound (0.65 g.).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04366164 |
| Source dataset | uspto-grants-1982_12 |
| ORD ID | ord-333f9d74e07042b2b610a8a9b7cae6c3 |
| Source note | uspto-grants-1982_12 |