HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-(4-Methylphenyl)prop-2-enenitrile → 4-Bromomethylcinnamonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-(4-Methylphenyl)prop-2-enenitrile | HCID 34242 | — |
| Reactant | N-bromobutanimide | HCID 67184 | — |
| Solvent | Carbon Tetrachloride | HCID 5943 | — |
| Product | 4-Bromomethylcinnamonitrile | HCID 54080447 | — |
Reaction Steps
88 g of 4-bromomethylcinnamonitrile (obtained by bromination of 4-methylcinnamonitrile with N-bromosuccinimide in carbon tetrachloride, and having a melting point of 105°-107° C.) are mixed with 256 g of triethylphosphite. The mixture is then slowly heated to 150° C. with stirring, and then stirred for 3 hours at this temperature. Excess phosphite is then removed in vacuo, affording the crude phosphonate of the formula ##STR68## in the form of a light brown oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04366189 |
| Source dataset | uspto-grants-1982_12 |
| ORD ID | ord-5f13d88c67494bdf84c0566407e9e67d |
| Source note | uspto-grants-1982_12 |