Sodium borohydride → Diniconazole

Participants

Reaction Steps

To 50 cc of a methanol solution containing 3.2 g of (E)-1-(2,4-dichlorophenyl)-2-(1,2,4-triazol-1-yl)-4,4-dimethyl-1-penten-3-one (melting point 92°-93° C.) characterized by the NMR spectrum shown below, was added 0.5 g of sodium borohydride, while cooling in ice. The mixture was then stirred at room temperature for 3 hours and treated as in Reference Example 1 to obtain 2.6 g of the captioned compound melting at 148°-149° C.

Provenance & Evidence