HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonia → N,N',N"-Tris[4-[[4-O-(alpha-D-glucopyranosyl)-beta-D-glucopyranosyl]thio]phenyl]-1,3,5-benzenetricarboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonia | HCID 222 | — |
| Reactant | N,N',N"-Tris[4-[[2,3,6-tri-O-acetyl-4-O-(2,3,4,6-tetra-O-acetyl-alpha-D-glucopyranosyl)-beta-D-glucopyranosyl]thio]phenyl]-1,3,5-benzenetricarboxamide | HCID 53908218 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | N,N',N"-Tris[4-[[4-O-(alpha-D-glucopyranosyl)-beta-D-glucopyranosyl]thio]phenyl]-1,3,5-benzenetricarboxamide | HCID 54214922 | 86.8% |
Reaction Steps
A solution of 2.56 g of N,N',N"-tris-[4-[[2,3,6-tri-O-acetyl-4-O-(2,3,4,6-tetra-O-acetyl-α-D-glucopyranosyl)-β-D-glucopyranosyl]thio]phenyl]-1,3,5-benzenetricarboxamide in 35 ml of methanol saturated with ammonia at 0° C. was allowed to stand at ambient temperature for 6 hours. The solution was clarified by filtration and taken to dryness. The residual material was triturated with absolute ethanol and filtered giving 1.4 g of the desired intermediate as a cream-colored powder.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04435387 |
| Source dataset | uspto-grants-1984_03 |
| ORD ID | ord-5f18a497d701426c9e3ab9b4aca0267d |
| Source note | uspto-grants-1984_03 |