HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Prednisolone → 11beta,17-Dihydroxy-21-methoxyacetoxy-1,4-pregnadiene-3,20-dione
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Prednisolone | HCID 5755 | — |
| Edukt | Methoxyacetyl chloride | HCID 96623 | — |
| Lösungsmittel | Pyridine | HCID 1049 | — |
| Produkt | 11beta,17-Dihydroxy-21-methoxyacetoxy-1,4-pregnadiene-3,20-dione | HCID 56613993 | — |
Reaktionsschritte
A solution of 10.0 g of 11β,17,21-trihydroxy-1,4-pregnadiene-3,20-dione in pyridine is reacted analogously to Example 1(a) with methoxyacetic acid chloride, worked up, and purified, thus isolating 10.3 g of 11β,17-dihydroxy-21-methoxyacetoxy-1,4-pregnadiene-3,20-dione.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US04435390 |
| Quelldatensatz | uspto-grants-1984_03 |
| ORD ID | ord-3abc6e147f7a4e7f835636401458d6ea |
| Quellennotiz | uspto-grants-1984_03 |