HuagongsheHuagongshe Chemistry Print Report · For research reference only
Prednisolone → 21-Ethoxyacetoxy-11beta,17-dihydroxy-1,4-pregnadiene-3,20-dione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Prednisolone | HCID 5755 | — |
| Reactant | Ethoxyacetyl chloride | HCID 84189 | — |
| Product | 21-Ethoxyacetoxy-11beta,17-dihydroxy-1,4-pregnadiene-3,20-dione | HCID 70487098 | — |
Reaction Steps
10.0 g of 11β,17,21-trihydroxy-1,4-pregnadiene-3,20-dione is reacted analogously to Example 2(a) with ethoxyacetic acid chloride, worked up, and purified, thus isolating 10.4 g of 21-ethoxyacetoxy-11β,17-dihydroxy-1,4-pregnadiene-3,20-dione.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04435390 |
| Source dataset | uspto-grants-1984_03 |
| ORD ID | ord-c7b2d5a903704a85973f0047e3d6af43 |
| Source note | uspto-grants-1984_03 |