Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Methylprednisolone → 21-Ethoxyacetoxy-11beta,17-dihydroxy-6alpha-methyl-1,4-pregnadiene-3,20-dione
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Methylprednisolone | HCID 6741 | — |
| 반응물 | Ethoxyacetyl chloride | HCID 84189 | — |
| 생성물 | 21-Ethoxyacetoxy-11beta,17-dihydroxy-6alpha-methyl-1,4-pregnadiene-3,20-dione | HCID 13135585 | — |
반응 단계
As described in Example 2(a), 15.0 g of 11β,17,21-trihydroxy-6α-methyl-1,4-pregnadiene-3,20-dione is reacted with ethoxyacetic acid chloride, worked up, and purified, thus isolating 15.6 g of 21-ethoxyacetoxy-11β,17-dihydroxy-6α-methyl-1,4-pregnadiene-3,20-dione, mp 229° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04435390 |
| 출처 데이터셋 | uspto-grants-1984_03 |
| ORD ID | ord-5509af00ac2440539bb076358467db49 |
| 출처 메모 | uspto-grants-1984_03 |