HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dihydrocoumarin → 4-(2,3-Epoxypropoxy)-1-oxoindane
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dihydrocoumarin | HCID 660 | — |
| Reactant | Epichlorohydrin | HCID 7835 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | 4-Hydroxy-1-indanone | HCID 590547 | — |
| Reactant | Aluminum(III) Chloride | HCID 6451240 | — |
| Product | 4-(2,3-Epoxypropoxy)-1-oxoindane | HCID 12831122 | — |
Reaction Steps
3,4-Dihydrocumarine is allowed to react with anhydrous aluminum chloride at 200° C. and the resulting 4-hydroxyindanone is allowed to react with epichlorohydrin in an aqueous solution of sodium hydroxide to give 4-(2,3-epoxypropoxy)-1-indanone (cf. Japanese Patent No. Sho-48-817).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04435397 |
| Source dataset | uspto-grants-1984_03 |
| ORD ID | ord-ee2b835f7af9431b9479a4195074c11e |
| Source note | uspto-grants-1984_03 |