HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → HCID 13305202, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | Epibromohydrin | HCID 18430 | — |
| Reactant | 5-Methyl-8-hydroxycoumarin | HCID 3080784 | — |
| Solvent | Methyl Ethyl Ketone | HCID 6569 | — |
| Product | HCID 13305202 | HCID 13305202 | — |
Reaction Steps
5-Methyl-8-hydroxycumarin (synthesized from isovanilin in 4 steps) is allowed to react with epibromohydrin in methyl ethyl ketone in the presence of potassium carbonate to give 5-methyl-8-(2,3-epoxypropoxy)-cumarin [cf. Chem. Phar. Bull. 20,205 (1972)].
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04435397 |
| Source dataset | uspto-grants-1984_03 |
| ORD ID | ord-e155ae9a0aaf4705bf9f595437cc08f1 |
| Source note | uspto-grants-1984_03 |