HuagongsheHuagongshe Chemistry Print Report · For research reference only
Piperidine → HCID 23316492, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Piperidine | HCID 8082 | — |
| Reactant | HCID 23316486 | HCID 23316486 | — |
| Solvent | Hexamethylphosphoramide | HCID 12679 | — |
| Product | HCID 23316492 | HCID 23316492 | 80.9% |
Reaction Steps
420 mg of 5-chloro-6-nitro-beta-carboline-3-carboxylic-acid-ethylester and 100 mg of piperidine in 10 ml of hexamethylphosphorotriamide are heated for 2 h to 80° C. After the solvent is distilled off, the residue is chromatographed on silica gel with methylene-chloride/ethanol. 350 mg of 5-piperidino-6-nitro-beta-carboline-3-carboxylic-acid-ethylester with a m.p. of 307° C. (decomposition) is obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04435403 |
| Source dataset | uspto-grants-1984_03 |
| ORD ID | ord-f2e9d245a19e47fa91b786238b0bbf26 |
| Source note | uspto-grants-1984_03 |