HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → 6-Chloro-5-methyl-4-[2-(2-methyl-4-n-pentylphenoxy)ethylamino]pyrimidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 4,6-Dichloro-5-methylpyrimidine | HCID 818860 | — |
| Reactant | 2-(2-Methyl-4-pentylphenoxy)ethylamine | HCID 15588031 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | 6-Chloro-5-methyl-4-[2-(2-methyl-4-n-pentylphenoxy)ethylamino]pyrimidine | HCID 13075462 | — |
Reaction Steps
To a solution of 3.2 g (0.02 mol) of 4,6-dichloro-5-methylpyrimidine in 50 ml of toluene were added 2.0 g (0.02 mol) of triethylamine and 4.4 g (0.02 mol) of 2-(2-methyl-4-n-pentylphenoxy)ethylamine. The mixture was then refluxed with stirring for 5 hours.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04435402 |
| Source dataset | uspto-grants-1984_03 |
| ORD ID | ord-d8e373fc8b09465d848e2d12e6c5f9b6 |
| Source note | uspto-grants-1984_03 |