Methyl iodide → HCID 20468253, compound
Reaction equation
[NH:1]1[CH2:6][CH2:5][CH2:4][CH:3]([C:7]2[CH:15]=[CH:14][CH:13]=[C:12]3[C:8]=2[CH2:9][C:10](=[O:16])[NH:11]3)[CH2:2]1.[CH3:17]I>>[CH3:17][N:1]1[CH2:6][CH2:5][CH2:4][CH:3]([C:7]2[CH:15]=[CH:14][CH:13]=[C:12]3[C:8]=2[CH2:9][C:10](=[O:16])[NH:11]3)[CH2:2]1Participants
3
Procedure
Using the procedure of Example 3, 1,3-dihydro-4-(piperidin-3-yl)-2H-indole-2-one and methyl iodide were reacted to obtain 1,3-dihydro-4-(1-methyl-piperidin-3-yl)-2H-indole-2-one which melted at 160° C. after crystallization from benzene.
Workup
- customwere reacted
Sources & evidence
- ORD record
- ord-7036348a656542e3b4948895de83b6dc
- Source dataset
- uspto-grants-1984_03
- Patent number
- US04435408
Reaction notes
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