Nitric Acid → HCID 13343741, compound

HRID 1903150Notes

Reaction equation

HRID 1903150 reaction equation
[CH3:1][CH:2]1[O:6][C:5]2[CH:7]=[CH:8][CH:9]=[CH:10][C:4]=2[O:3]1.[N+:11]([O-])([OH:13])=[O:12]>C(O)(=O)C>[CH3:1][CH:2]1[O:6][C:5]2[CH:7]=[CH:8][C:9]([N+:11]([O-:13])=[O:12])=[CH:10][C:4]=2[O:3]1

Participants

4

Reactant 2

HCID 944Nitric AcidHCID 841672-Methyl-2H-1,3-benzodioxole

Product 1

HCID 13343741HCID 13343741, compoundYield 79.6%

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent2×

Procedure

27.2 g of 2-methyl-1,3-benzodioxole, dissolved in 150 ml of glacial acetic acid, were nitrated at 15°-25° C. with 18 ml of nitric acid (d=1.4) in 50 ml of glacial acetic acid. The precipitated crystals were removed by filtration under suction and recrystallized from methanol. There were obtained 28.8 g (79.6% of theory) of 2-methyl-5-nitro-1,3-benzodioxole of melting point 84°-95° C. after sublimation at 0.1 mm/70° C.

Workup

  1. customThe precipitated crystals were removed by filtration under suction
  2. customrecrystallized from methanol

Sources & evidence

ORD record
ord-85e5dd092d2b4dadaeedcdf93015c86b
Source dataset
uspto-grants-1984_03
Patent number
US04435406

Reaction notes

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