HuagongsheHuagongshe Chemistry Print Report · For research reference only
8-nitro-3,4-dihydro-2H-1,5-benzodioxepin-7-amine → 2H-1,5-Benzodioxepin-7,8-diamine, 3,4-dihydro-
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 8-nitro-3,4-dihydro-2H-1,5-benzodioxepin-7-amine | HCID 4252033 | — |
| Catalyst | Nickel | HCID 935 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 2H-1,5-Benzodioxepin-7,8-diamine, 3,4-dihydro- | HCID 9120713 | 88.1% |
Reaction Steps
10.2 g of 7-amino-8-nitro-3,4-dihydro-2H-1,5-benzodioxepine were hydrogenated in 500 ml of methanol with Raney-nickel. After separating the catalyst, the solution was evaporated and the residue was recrystallized from ethyl acetate/petroleum either (low boiling). 7.7 g of 3,4-dihydro-2H-1,5-benzodioxepine-7,8-diamine (88.0% of theory) of melting point 97°-102° C. were obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04435406 |
| Source dataset | uspto-grants-1984_03 |
| ORD ID | ord-b37dd8e3ca7d44a09f6e50e3c2be8ac6 |
| Source note | uspto-grants-1984_03 |