HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Nitrobenzoyl chloride → HCID 13300595, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Nitrobenzoyl chloride | HCID 8502 | — |
| Reactant | Aluminum(III) Chloride | HCID 6451240 | — |
| Reactant | Ethyl 6,7-dichloro-2,3-dihydro-1-benzofuran-2-carboxylate | HCID 12747889 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 13300595 | HCID 13300595 | — |
Reaction Steps
A solution of ethyl 6,7-dichloro-2,3-dihydrobenzofuran-2-carboxylate (10.0 g.) and p-nitrobenzoyl chloride (14.2 g.) in methylene chloride (40 ml.) was placed on a cold water bath with mechanical agitation and treated with aluminum chloride (15.3 g.) portionwise over 5 minutes. The bath was then heated at 80°-90° C. for 1 hour and removed, and the mixture diluted with 100 ml. of methylene chloride.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04435422 |
| Source dataset | uspto-grants-1984_03 |
| ORD ID | ord-1c1fffb9dde74525b956d9e7f2e0654d |
| Source note | uspto-grants-1984_03 |