HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Fluorobenzoyl chloride → 3-(m-Fluorobenzoyl)-1-(p-chlorophenyl)-3-azabicyclo[3.1.0]hexane
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Fluorobenzoyl chloride | HCID 74376 | — |
| Reactant | 1-(4-Chlorophenyl)-3-azabicyclo[3.1.0]hexane | HCID 10130331 | — |
| Reactant | 3-(m-Fluorobenzyl)-1-(p-chlorophenyl)-3-azabicyclo[3.1.0]hexane hydrochloride | HCID 20468405 | — |
| Product | 3-(m-Fluorobenzoyl)-1-(p-chlorophenyl)-3-azabicyclo[3.1.0]hexane | HCID 20468363 | — |
Reaction Steps
Likewise, 3-(m-fluorobenzoyl)-1-(p-chlorophenyl)-3-azabicyclo[3.1.0]hexane is prepared from 1-(p-chlorophenyl)-3-azabicyclo[3.1.0]hexane and m-fluorobenzoylchloride, then converted as above to 3-(m-fluorobenzyl)-1-(p-chlorophenyl)-3-azabicyclo[3.1.0]hexane hydrochloride, m.p. 241°-244° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04435419 |
| Source dataset | uspto-grants-1984_03 |
| ORD ID | ord-a2e62ec5899c4088a1a57a5e8257b788 |
| Source note | uspto-grants-1984_03 |