Benzoyl Peroxide → Ethyl 2-bromo-2-(3,4-dichlorophenyl)acetate

Participants

Reaction Steps

In a three-necked flask fitted with a Nichrome stirrer and a relux condenser is placed 7.0 g. of ethyl 3,4-dichlorophenylacetate, 5.9 g. of N-bromosuccinimide, 0.1 g. of benzoyl peroxide and 150 ml. of carbon tetrachloride. The reaction mixture is heated at reflux for 18 hours, cooled and filtered. The carbon tetrachloride filtrate is concentrated under reduced pressure to give a deep orange liquid. Vacuum distillation at 115°-120° C. (0.5 mm) gives ethyl α-bromo-3,4-dichlorophenylacetate as a pale yellow liquid.

Provenance & Evidence