HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-bromobutanimide → Methyl alpha-bromo-2-chlorophenylacetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-bromobutanimide | HCID 67184 | — |
| Reactant | Methyl (2-chlorophenyl)acetate | HCID 93683 | — |
| Catalyst | Hydrogen Bromide | HCID 260 | — |
| Solvent | Carbon Tetrachloride | HCID 5943 | — |
| Product | Methyl alpha-bromo-2-chlorophenylacetate | HCID 10730282 | — |
Reaction Steps
A stirred mixture of 36.9 g. of methyl o-chlorophenylacetate, 36.0 g. of N-bromosuccinimide, and 2 drops of 48% hydrobromic acid in 500 ml. of carbon tetrachloride is refluxed for 20 hours and then filtered through magnesium silicate. Evaporation under reduced pressure gives methyl α-bromo-o-chlorophenylacetate as a straw-colored liquid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04435419 |
| Source dataset | uspto-grants-1984_03 |
| ORD ID | ord-5d25e86f9cc14ce1bdc85697fd033999 |
| Source note | uspto-grants-1984_03 |