Acetyl chloride → HCID 20468403, compound

HRID 1903268Notes

Reaction equation

HRID 1903268 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]23[CH2:13][CH:12]2[CH2:11][NH:10][CH2:9]3)=[CH:4][CH:3]=1.[C:14](Cl)(=[O:16])[CH3:15]>>[C:14]([N:10]1[CH2:11][CH:12]2[C:8]([C:5]3[CH:4]=[CH:3][C:2]([Cl:1])=[CH:7][CH:6]=3)([CH2:13]2)[CH2:9]1)(=[O:16])[CH3:15]

Participants

3

Reactant 2

HCID 6367Acetyl chlorideHCID 101303311-(4-Chlorophenyl)-3-azabicyclo[3.1.0]hexane

Product 1

HCID 20468403HCID 20468403, compound

Procedure

Using the method of Example 15, 1-(p-chlorophenyl)-3-azabicyclo[3.1.0]hexane (Example 1) is reacted with acetyl chloride to give 3-acetyl-1-(p-chlorophenyl)-3-azabicyclo[3.1.0]hexane and then is converted to 1-(p-chlorophenyl)-3-ethyl-3-azabicyclo[3.1.0]hexane which is obtained as a brown oil.

Sources & evidence

ORD record
ord-b8ad951be2f645269d1a66757cbea470
Source dataset
uspto-grants-1984_03
Patent number
US04435419

Reaction notes

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