4-Methyloxybenzyl chloride → HCID 20468544, compound

HRID 1903316Notes

Reaction equation

HRID 1903316 reaction equation
[NH2:1][C:2]1[N:7]=[C:6]2[N:8]=[CH:9][C:10]([CH2:11][NH2:12])=[C:5]2[C:4](=[O:13])[N:3]=1.[CH3:14][O:15][C:16]1[CH:23]=[CH:22][C:19]([CH2:20]Cl)=[CH:18][CH:17]=1>>[NH2:1][C:2]1[N:7]=[C:6]2[N:8]=[CH:9][C:10]([CH2:11][NH:12][CH2:20][C:19]3[CH:22]=[CH:23][C:16]([O:15][CH3:14])=[CH:17][CH:18]=3)=[C:5]2[C:4](=[O:13])[N:3]=1

Participants

3

Reactant 2

HCID 699934-Methyloxybenzyl chlorideHCID 202463772-Amino-5-aminomethylpyrrolo[2,3-d]pyrimidin-4-one

Product 1

HCID 20468544HCID 20468544, compound

Procedure

By the same procedure as Example 5, 162 mg of the above-identified compound is synthesized from 252 mg of 2-amino-5-aminomethylpyrrolo[2,3-d]pyrimidin-4-one (dihydrochloride) and 157 mg of p-methoxybenzyl chloride.

Sources & evidence

ORD record
ord-6017140c43e644a1afd2db571e4109ed
Source dataset
uspto-grants-1984_03
Patent number
US04435569

Reaction notes

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