Bromine → HCID 13268202, compound

HRID 1903380Notes

Reaction equation

HRID 1903380 reaction equation
[CH3:1][C:2]([CH2:8][CH3:9])([CH2:6][CH3:7])[C:3](=[O:5])[CH3:4].[Br:10]Br.[Cl-].[Al+3].[Cl-].[Cl-]>C(OCC)C>[Br:10][CH2:4][C:3](=[O:5])[C:2]([CH3:1])([CH2:8][CH3:9])[CH2:6][CH3:7]

Participants

5

Reactant 3

HCID 24408BromineHCID 1405902-Pentanone, 3-ethyl-3-methyl-HCID 6451240Aluminum(III) Chloride

Product 1

HCID 13268202HCID 13268202, compound

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

To a solution of 9.0 g of 3-methyl-3-ethyl-2-pentanone in 100 ml diethyl ether cooled to about 0°-5° C. with an ice bath was added 3.6 ml bromine. The reaction mixture was allowed to warm to room temperature and a catalytic amount of aluminum chloride was added. The mixture was stirred for 30 minutes and washed with water and a saturated sodium bicarbonate solution. The organic phase was separated, dried over anhydrous sodium sulfate and evaporated under vacuum to provide an oil. The oil was distilled under vacuum to provide 6.3 g of product. bp=100°-114° C. at 16 mm.

Workup

  1. washwashed with water
  2. customThe organic phase was separated
  3. dry with materialdried over anhydrous sodium sulfate
  4. customevaporated under vacuum
  5. customto provide an oil
  6. distillationThe oil was distilled under vacuum

Sources & evidence

ORD record
ord-45f38bed5bd047d0ab1e4bec698e7d67
Source dataset
uspto-grants-1984_03
Patent number
US04436549

Reaction notes

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