反应详情

To a solution (20 ml) of 6-(12-acetoxydodecyl)-2,3-dimethoxy-5-methylphenol (1.1 g) in dimethylforamide is added bis(salicylidene)ethylenediiminocobalt(II) (40 mg), and the mixture is stirred at room temperature in an oxygen gas stream at atmospheric pressure for 72 hours. The solvent is distilled off and the product is extracted with ether. The ether layer is washed with water and dried over anhydrous sodium sulfate, and solvent is distilled off to give crude crystals. Recrystallization from ether-hexane (1:1) gives orange-yellow needles of 6-(12-acetoxydodecyl)-2,3-dimethoxy-5-methyl-1,4-benzoquinone (0.84 g). m.p. 47° C.

1. distillationThe solvent is distilled off
2. extractionthe product is extracted with ether
3. washThe ether layer is washed with water
4. dry with materialdried over anhydrous sodium sulfate, and solvent
5. distillationis distilled off
6. customto give crude crystals
7. customRecrystallization from ether-hexane (1:1)