HRID1903529

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID73086

L-Serine, N-glycyl-

C5H10N2O4

结构：CCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC(C)(C)C

HCID21769587

未命名化合物

PRODUCTS

生成物

结构：CCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)NCC(=O)N[C@@H](CO)C(=O)O

HCID54571602

未命名化合物

收率 61.5%

PROCEDURE

实验过程

Starting from tert-butyl 3-dodecanoyloxytetradecanoate (165 mg) prepared by the method described in Preparation 3-(2) and N-glycyl-L-serine (162 mg), N-[N-(3-dodecanoyloxytetradecanoyl)glycyl]-L-serine (120 mg) was obtained as an amorphous powder according to similar manner to that of Example 1.

WORKUP

后处理

customprepared by the method

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-2ff437e1cea54581913aae07660c0eae
来源数据集: uspto-grants-1984_03
DOI: 10.6084/m9.figshare.5104873.v1
专利: US04436726
来源说明: uspto-grants-1984_03

反应 SMILES

[C:1]([O:14][CH:15]([CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH3:34])[CH2:16][C:17]([O:19]C(C)(C)C)=O)(=[O:13])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH3:12].[NH2:35][CH2:36][C:37]([NH:39][C@H:40]([C:43]([OH:45])=[O:44])[CH2:41][OH:42])=[O:38]>>[C:1]([O:14][CH:15]([CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH3:34])[CH2:16][C:17]([NH:35][CH2:36][C:37]([NH:39][C@H:40]([C:43]([OH:45])=[O:44])[CH2:41][OH:42])=[O:38])=[O:19])(=[O:13])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH3:12]