HRID1903539

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID6287

L-Valine

C5H11NO2

结构：CCCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCCCCCC)CC(=O)O

HCID13489028

3-(Hexadecanoyloxy)octadecanoic acid

C34H66O4

PRODUCTS

生成物

结构：CCCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCCCCCC)CC(=O)N[C@H](C(=O)O)C(C)C

HCID53729937

N-[3-(Hexadecanoyloxy)octadecanoyl]-L-valine

C39H75NO5

收率 62.6%

PROCEDURE

实验过程

Starting from 3-hexadecanoyloxyoctadecanoic acid (10.8 g) prepared by the method described in Preparation 2 and L-valine (5.85 g), N-(3-hexadecanoyloxyoctadecanoyl)-L-valine (8 g) was obtained as crystals according to a similar manner to that of Example 6.

WORKUP

后处理

customprepared by the method

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-0c9a9ed305bb419185ca0479af480b18
来源数据集: uspto-grants-1984_03
DOI: 10.6084/m9.figshare.5104873.v1
专利: US04436726
来源说明: uspto-grants-1984_03

反应 SMILES

[C:1]([O:18][CH:19]([CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][CH2:37][CH3:38])[CH2:20][C:21]([OH:23])=O)(=[O:17])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH3:16].[NH2:39][C@H:40]([C:44]([OH:46])=[O:45])[CH:41]([CH3:43])[CH3:42]>>[C:1]([O:18][CH:19]([CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][CH2:37][CH3:38])[CH2:20][C:21]([NH:39][C@H:40]([C:44]([OH:46])=[O:45])[CH:41]([CH3:43])[CH3:42])=[O:23])(=[O:17])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH3:16]