HRID1903546

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：CCCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCCCCC)C(=O)O

HCID13371862

2-(Hexadecanoyloxy)hexadecanoic acid

C32H62O4

HCID18649800

未命名化合物

PRODUCTS

生成物

结构：CCCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCCCCC)C(=O)NCCC(=O)N[C@H](C(=O)O)[C@@H](C)O

HCID54508912

未命名化合物

收率 86%

PROCEDURE

实验过程

Starting from 2-hexadecanoyloxyhexadecanoic acid (200 mg) prepared by the method described in Preparation 7 and N-β-alanyl-L-threonine (190 mg), N-[N-(2-hexadecanoyloxyhexadecanoyl)-β-alanyl]-L-threonine (230 mg) was obtained as crystals according to a similar manner to that of Example 6.

WORKUP

后处理

customprepared by the method

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-5f6ac18f0e9d41e8a129740fe91e55a4
来源数据集: uspto-grants-1984_03
DOI: 10.6084/m9.figshare.5104873.v1
专利: US04436726
来源说明: uspto-grants-1984_03

反应 SMILES

[C:1]([O:18][CH:19]([CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH3:36])[C:20]([OH:22])=O)(=[O:17])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH3:16].[NH2:37][CH2:38][CH2:39][C:40]([NH:42][C@H:43]([C:47]([OH:49])=[O:48])[C@@H:44]([CH3:46])[OH:45])=[O:41]>>[C:1]([O:18][CH:19]([CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH3:36])[C:20]([NH:37][CH2:38][CH2:39][C:40]([NH:42][C@H:43]([C:47]([OH:49])=[O:48])[C@@H:44]([CH3:46])[OH:45])=[O:41])=[O:22])(=[O:17])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH3:16]