HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Bromopyrimidine → 2,3-Piperazinedione, 1,4-bis((4-(2-pyrimidinylamino)phenyl)methyl)-
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Bromopyrimidine | HCID 78345 | — |
| Reactant | HCID 12752249 | HCID 12752249 | — |
| Product | 2,3-Piperazinedione, 1,4-bis((4-(2-pyrimidinylamino)phenyl)methyl)- | HCID 3060252 | 14.7% |
Reaction Steps
The 1,4-bis(4-aminobenzyl)-2,3-dioxopiperazine was reacted with 2-bromopyrimidine in the same manner as in Example 6-(1) to obtain 1,4-bis[4-(2-pyrimidinylamino)benzyl]-2,3-dioxopiperazine (14.7% yield).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04436921 |
| Source dataset | uspto-grants-1984_03 |
| ORD ID | ord-53eb0cd22d374444b0dde06c288550b3 |
| Source note | uspto-grants-1984_03 |