HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phenylurea → HCID 13246746, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phenylurea | HCID 6145 | — |
| Reactant | 2-Methylbenzenesulfonic acid | HCID 6925 | — |
| Reactant | Cyclohexane | HCID 8078 | — |
| Reactant | 3-Thiophenecarboxylic acid, tetrahydro-4-oxo-, methyl ester | HCID 98424 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 13246746 | HCID 13246746 | — |
Reaction Steps
14.4 parts by weight of methyl 3-keto-3,4-dihydrothiophene-4-carboxylate, 16.1 parts by weight of phenylurea and 0.5 part by weight of toluenesulfonic acid in 90 parts by weight of cyclohexane were refluxed for 3 hours, while stirring, in an apparatus equipped with a water separator. The mixture was cooled, and the residue was then filtered off under suction and recrystallized from ethanol. 16.1 parts by weight of N-phenyl-N'-(3-methoxycarbonyl-2,5-dihydrothien-4-yl)-urea of melting point 182°-184° C. were obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04437878 |
| Source dataset | uspto-grants-1984_03 |
| ORD ID | ord-b79b72c49c2c413ba2cce1d2a83df410 |
| Source note | uspto-grants-1984_03 |