反应详情

To a solution of 3-(3-phenylpropyl)aniline (11.6 g) in 100 ml of toluene was dropwise added a solution of phosgene (20 g) in 100 ml of toluene at 10°-20° C. The resultant mixture was gradually heated and, after refluxed for 30 minutes, allowed to cool to room temperature. The solvent was removed under reduced pressure, and the residue was distilled under reduced pressure to give 11.6 g of 3-(3-phenylpropyl)phenyl isocyanate (yield, 89%). B.P. 121°-125° C./0.2 mmHg.

1. temperatureafter refluxed for 30 minutes
2. customThe solvent was removed under reduced pressure
3. distillationthe residue was distilled under reduced pressure