1,2-Dibromoethane → HCID 20466799, compound

Participants

Reaction Steps

45.2 g (0.1 mole) of α-(n-dodecyl)-α-(2-bromoethyl)-3,4-dimethoxyphenyl-acetonitrile (obtained by condensation of α-dodecyl-3,4-dimethoxy-phenylacetonitrile with 1,2-dibromoethane in toluene solution in the presence of lithium diisopropylamide) and 41.8 g of β-(N-ethyl)-3,4-dimethoxyphenethylamine were heated at 150° C. in an oilbath for two hours. 250 ml of toluene were added while the mixture was still hot and the precipitate of β-(N-ethyl)-3,4-dimethoxy-phenethylamine hydrobromide which separated out was filtered off with suction.

Provenance & Evidence