Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Boc-Tyr-(D)Ala-Gly-OBzl → Boc-tyr-D-ala-gly-OH
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Boc-Tyr-(D)Ala-Gly-OBzl | HCID 15567201 | — |
| 용매 | Palladium | HCID 23938 | — |
| 용매 | Methanol--water (1/1) | HCID 22242641 | — |
| 생성물 | Boc-tyr-D-ala-gly-OH | HCID 7272028 | — |
반응 단계
12 g of Boc-Tyr-(D)Ala-Gly-OBzl are dissolved in a mixture of methanol/H2O (9:1) and hydrogenated in the presence of Pd-C at normal pressure and room temperature. The mixture is filtered off from the catalyst, reduced in volume and crystallised from methanol/CH2Cl2 /ether. Decomp. 110°.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04438103 |
| 출처 데이터셋 | uspto-grants-1984_03 |
| ORD ID | ord-bb05406f601f43229aaf95aec66b1c9d |
| 출처 메모 | uspto-grants-1984_03 |