Phosgene → HCID 19852896, compound

Participants

Reaction Steps

A solution of 125.3 g of 4-isopropoxycarbonylaniline in 160 ml of dioxane was added dropwise within 30 minutes at 0°-10° C. to a solution of 100 ml of phosgene in 300 ml of dioxane while stirring. The reaction mixture was then stirred at 20° C. for 30 minutes and then heated to boiling; the solvent was distilled off and the residue was distilled under reduced pressure. The desired 4-isopropoxycarbonylphenyl isocyanate was obtained in a yield of 136.8 g; boiling point 87°-88° C./0.2 mm.

Provenance & Evidence