Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1904015Generated: October 31, 2026

(2-Nitrophenyl)acetic acid → Ethyl 2-(2-aminophenyl)acetate

https://huagongshe.com/reaction/1904015

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(2-Nitrophenyl)acetic acidHCID 77337—
ReactantEthanol hydrochlorideHCID 21887872—
CatalystPalladiumHCID 23938—
SolventEthanolHCID 702—
ProductEthyl 2-(2-aminophenyl)acetateHCID 5743383—

Reaction Steps

In 15% hydrogen chloride-ethanol, m- or o-nitrophenylacetic acid was ethyl-esterified and the resulting ethyl ester was hydrogenated with palladium catalyst in ethanol to give m- or o-aminophenylacetic acid ethyl ester.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04439448
Source datasetuspto-grants-1984_03
ORD IDord-ba50d1f2bf4f4509a0a84081c11cbc00
Source noteuspto-grants-1984_03