HCID 22826111, compound → HCID 22826112, compound

Participants

Reaction Steps

0.9 g of N-palmitoyl-S-[2(R),3(R),4-trihydroxybutyl]-(L)-cysteine-benzhydryl ester in a mixture of 3 ml of trifluoroacetic acid and 12 ml of methylene chloride is allowed to stand for 2 hours at room temperature. The reaction mixture is then evaporated to dryness; the residue is triturated with ice-water, filtered off with suction and the solid substance is dried. It is then extracted with ligroin, and recrystallised from acetone to yield colourless crystals of N-palmitoyl-S-[2(R),3(R),4-trihydroxy-butyl]-(L)-cysteine, m.p. 76°-76.5°, having the specific rotation [α]D20 =-5° (c=0.819, dioxane).

Provenance & Evidence