HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzoyl Peroxide → 1-Fluoro-2-phthalimido-5-bromo-3-pentene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzoyl Peroxide | HCID 7187 | — |
| Reactant | N-bromobutanimide | HCID 67184 | — |
| Reactant | 1-Fluoro-2-phthalimido-3-pentene | HCID 54534105 | — |
| Solvent | Carbon Tetrachloride | HCID 5943 | — |
| Product | 1-Fluoro-2-phthalimido-5-bromo-3-pentene | HCID 54481049 | — |
Reaction Steps
A mixture of 1-fluoro-2-phthalimido-3-pentene (800 mg, 3.4 mmoles) prepared as in Step C above, N-bromosuccinimide (612 mg. 3.4 mmoles), carbon tetrachloride (30 mL) and a few mg of benzoyl peroxide is heated under strong reflux during irradiation with a lamp (325 W) during one hour. After washing with water the organic phase is dried over magnesium sulfate and then concentrated under reduced pressure to yield 1-fluoro-2-phthalimido-5-bromo-3-pentene as a slightly yellow oil (1.06 g, quantitative yield).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04439619 |
| Source dataset | uspto-grants-1984_03 |
| ORD ID | ord-0788fea1dac54205b5eac8f7cf3c7bfc |
| Source note | uspto-grants-1984_03 |