HCID 131713457, compound → HCID 131713459, compound

Participants

Reaction Conditions

Reaction Steps

A mixture of 0.27 g of the product of Step A and 2 ml of 50% aqueous formic acid was stirred at 45° C. for 10 minutes and was thn evaporated to dryness. The residue was triturated with ether and 1.55 g of raw product were recovered which was dissolved in 0.5 ml of methanol. 5 ml of ether were added thereto to recover 0.14 g of the syn isomer of 3-acetoxymethyl-7-[2-(2-amino-4-thiazolyl-2-(phenylcarbonyloxyimino)-acetamido]-ceph-3-eme-4-carboxylic acid.

Provenance & Evidence