Trifluoroacetic acid → HCID 131713461, compound

Participants

Reaction Steps

A mixture of the product of Step B and 12 ml of trifluoroacetic acid was stirred for 30 minutes at room temperature and part of the acid was evaporated under reduced pressure. 120 ml of isopropyl ether were added thereto. Efflorescence occured and the mixture was occur filtered. The product was rinsed with isopropyl ether and dried to obtain the syn isomer of 3-acetoxymethyl-7-[2-(2-amino-4-thiazolyl)-2-(2-amino-2-thioxoethoxyimino)-acetamido]-ceph-3-eme-4-carboxylic acid identical to the product of Example 16.

Provenance & Evidence