Carbamic acid,n-[2-amino-5-[(2-methylpropyl)amino]-4-(trifluoromethyl)phenyl]-,1,1-dimethylethyl ester → {5-(Isobutyl-amino)-2-[3-oxo-3-(3-[1,2,4]triazol-1-yl-phenyl)-propionylamino]-4-trifluoromethyl-phenyl}-carbamic acid tert-butyl ester
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([NH:7][c:8]1[c:9]([NH2:23])[cH:10][c:11]([C:19]([F:20])([F:21])[F:22])[c:12]([NH:14][CH2:15][CH:16]([CH3:17])[CH3:18])[cH:13]1)=[O:24].[C:25]([CH3:27])([CH3:28])([O:29][C:30](=[O:26])[CH2:31][C:32]([c:33]1[cH:34][c:35](-[n:39]2[n:40][cH:41][n:42][cH:43]2)[cH:36][cH:37][cH:38]1)=[O:44])[CH3:45]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([NH:7][c:8]1[c:9]([NH:23][C:30](=[O:29])[CH2:31][C:32]([c:33]2[cH:34][c:35](-[n:39]3[n:40][cH:41][n:42][cH:43]3)[cH:36][cH:37][cH:38]2)=[O:44])[cH:10][c:11]([C:19]([F:20])([F:21])[F:22])[c:12]([NH:14][CH2:15][CH:16]([CH3:17])[CH3:18])[cH:13]1)=[O:24]Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-b86436bc61db45debaafe929904c833c
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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