HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethanol → N-(2-(2,5-Dimethyl-1H-pyrrol-1-yl)ethyl)acetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethanol | HCID 702 | — |
| Reactant | 2,5-Hexanedione | HCID 8035 | — |
| Reactant | HCID 21226596 | HCID 21226596 | — |
| Product | N-(2-(2,5-Dimethyl-1H-pyrrol-1-yl)ethyl)acetamide | HCID 13770049 | — |
Reaction Steps
171.2 g (1.5 mol) of acetonylacetone and 153.2 g (1.5 mol) of 1-acetylethylenediamine are heated under reflux in 1.8 l of ethanol for 3 h. The reaction mixture is concentrated, and the residue is recrystallized from toluene. Yield: 259.3 g (96% of theory), Melting point: 106°-107° C. Elemental analysis: C10H16N2O (180.25) calculated: C 66.6 H 8.9 N 15.5 0 8.9 found: C 66.8 H 8.8 N 15.6 0 8.9
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04837225 |
| Source dataset | uspto-grants-1989_06 |
| ORD ID | ord-f1e84a884cfe476a9344f97a51690bae |
| Source note | uspto-grants-1989_06 |