HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Carbonate → 2-t-butyl-4-chloro-5-(4-methoxymethoxybenzylthio)-3(2H)-pyridazinone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Carbonate | HCID 10340 | — |
| Reactant | 4-Chloro-2-(1,1-dimethylethyl)-5-mercapto-3(2H)-pyridazinone | HCID 13469242 | — |
| Reactant | 1-(Chloromethyl)-4-(methoxymethoxy)benzene | HCID 14671801 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 2-t-butyl-4-chloro-5-(4-methoxymethoxybenzylthio)-3(2H)-pyridazinone | HCID 14671802 | 32.9% |
Reaction Steps
In 10 ml of N,N-dimethylformamide were dissolved 0.94 g of 2-t-butyl-4-chloro-5-mercapto-3(2H)-pyridazinone and 0.8 g of 4-methoxymethoxybenzyl chloride, and then 0.55 g of anhydrous sodium carbonate was added thereto. The mixture was stirred overnight at room temperature. Then, procedures similar to those in Preparation Example 3 were carried out to obtain 520 mg of the aimed compound, m.p. 50.0°~54.0° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04837217 |
| Source dataset | uspto-grants-1989_06 |
| ORD ID | ord-66ec752446884def8d450c9ee98fc6bb |
| Source note | uspto-grants-1989_06 |