HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(2-Ethoxypropoxy)-benzyl bromide → 2-t-butyl-4-chloro-5-[4-(2-ethoxypropoxy)benzyloxy]-3(2H)-pyridazinone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(2-Ethoxypropoxy)-benzyl bromide | HCID 14671815 | — |
| Reactant | 2-tert-Butyl-4-chloro-5-hydroxypyridazin-3(2H)-one | HCID 54686946 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 2-t-butyl-4-chloro-5-[4-(2-ethoxypropoxy)benzyloxy]-3(2H)-pyridazinone | HCID 14671816 | 37.6% |
Reaction Steps
In 15 ml of N,N-dimethylformamide were dissolved 1.5 g of 2-t-butyl-4-chloro-5-hydroxy-3(2H)-pyridazinone and 2.2 g of 4-(2-ethoxypropoxy)-benzyl bromide, and the resulting solution was heated under stirring on an oil bath at 80° to 90° C. for 3 hours. Then, similarly to the procedures in Preparation Example 2, 1.1 g of the aimed product was obtained as an oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04837217 |
| Source dataset | uspto-grants-1989_06 |
| ORD ID | ord-a735cf5539504175b4296e1f51bd3cf9 |
| Source note | uspto-grants-1989_06 |