HCID 14671817, compound → HCID 14671818, compound

HRID 1904246Notes

Reaction equation

HRID 1904246 reaction equation
[C:1]([N:5]1[C:10](=[O:11])[C:9]([Cl:12])=[C:8]([OH:13])[CH:7]=[N:6]1)([CH3:4])([CH3:3])[CH3:2].[CH3:14][C:15]([CH3:30])([O:21][C:22]1[CH:29]=[CH:28][C:25]([CH2:26]Br)=[CH:24][CH:23]=1)[CH2:16][O:17][CH2:18][CH2:19][CH3:20]>>[C:1]([N:5]1[C:10](=[O:11])[C:9]([Cl:12])=[C:8]([O:13][CH2:26][C:25]2[CH:24]=[CH:23][C:22]([O:21][C:15]([CH3:14])([CH3:30])[CH2:16][O:17][CH2:18][CH2:19][CH3:20])=[CH:29][CH:28]=2)[CH:7]=[N:6]1)([CH3:4])([CH3:2])[CH3:3]

Participants

3

Reactant 2

HCID 14671817HCID 14671817, compoundHCID 546869462-tert-Butyl-4-chloro-5-hydroxypyridazin-3(2H)-one

Product 1

HCID 14671818HCID 14671818, compoundYield 50.3%

Procedure

By using 2.0 g of 2-t-butyl-4-chloro-5-hydroxy-3(2H)-pyridazinone and 3.0 g of 4-(1,1-dimethyl-2-propoxyethoxy)benzyl bromide and similarly to the procedures in Preparation Example 13, 2.1 g of the aimed product was obtained as an oil.

Workup

  1. customsimilarly to the procedures in Preparation Example 13

Sources & evidence

ORD record
ord-1f2ef76374cc437b9f5b95c3778b4539
Source dataset
uspto-grants-1989_06
Patent number
US04837217

Reaction notes

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