1,1'-Biphenyl, mixt. with 1,1'-oxybis(benzene) → HCID 20038764, compound

HRID 1904269Notes

Reaction equation

HRID 1904269 reaction equation
[C:1]([C:4](=[CH:10][NH:11][C:12]1[CH:13]=[N:14][NH:15][CH:16]=1)[C:5]([O:7]CC)=O)(=[O:3])[CH3:2].C1C=CC(C2C=CC=CC=2)=CC=1.C1C=CC(OC2C=CC=CC=2)=CC=1>>[C:1]([C:4]1[C:5](=[O:7])[C:13]2[NH:14][N:15]=[CH:16][C:12]=2[NH:11][CH:10]=1)(=[O:3])[CH3:2]

Participants

3

Reactant 2

HCID 246701,1'-Biphenyl, mixt. with 1,1'-oxybis(benzene)HCID 178471961HCID 178471961, compound

Product 1

HCID 20038764HCID 20038764, compoundYield 74%

Procedure

Ethyl 2-acetyl-3-(4-pyrazolylamino)acrylate (D13, 1.0 g, 4.5 mmol) was added to boiling Dowtherm A, and the solution was heated under reflux for 20 min. The mixture was allowed to cool and 60°-80° petroleum ether (100 ml) was added. The solid was filtered off and washed well with petroleum ether to give the title compound (590 mg, 74%), m.p.>320° C.

Workup

  1. temperaturethe solution was heated
  2. temperatureunder reflux for 20 min
  3. additionwas added
  4. filtrationThe solid was filtered off
  5. washwashed well with petroleum ether

Sources & evidence

ORD record
ord-68b55c522cd24ab4a8706d8573fb52e2
Source dataset
uspto-grants-1989_06
Patent number
US04837238

Reaction notes

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