反应详情

To a solution of 1.0 g of 1,3,5-trimethyl-N-(1,1,3-trimethyl-4-indanyl)pyrazolecarboxamide in 20 ml of dimethoxyethane was added 914 mg of 2,4-bis(methylthio)-1,3,2,4-dithiadiphosphetan-2,4-disulfide with stirring, followed by stirring for 10 hours at room temperature and for 1 hour at 50° C. After cooling, the reaction mixture was chromatographed on silica gel to obtain 0.89 g of 1,3,5-trimethyl-N-(1,1,3-trimethylindane-4-yl)pyrazole carbothioamide (yield 85%).

1. stirringby stirring for 10 hours at room temperature and for 1 hour at 50° C
2. temperatureAfter cooling
3. customthe reaction mixture was chromatographed on silica gel