Oxalic Acid → HCID 23047517, compound

Participants

Reaction Steps

A solution of 1-methyl-1,2,5,6-tetrahydropyridin-3-carboxamide oxime (200 mg; 1.29 mmol) in acetic anhydride (5 ml) was heated at 80° C. for 24 hours. After evaporation in vacuo the residue was dissolved in 4N NaOH (5 ml) and extracted with ether (3×25 ml). The ether phases were dried (MgSO4), filtered, and evaporated in vacuo. The residue was dissolved in ethanol (99.9%)(5 ml) and added to a solution of oxalic acid (100 mg; 1.1 mmol) in ethanol (99.9%)(5 ml). Addition of ether gave the title compound in a yield of 52%. M.P. 173°-174° C.

Provenance & Evidence