Nitric Acid → HCID 14450250, compound

HRID 1904368Notes

Reaction equation

HRID 1904368 reaction equation
[CH3:1][C:2]1[CH:3]=[C:4]([N:8]2[CH:12]=[N:11][N:10]=[N:9]2)[CH:5]=[CH:6][CH:7]=1.[N+:13]([O-])([OH:15])=[O:14]>>[CH3:1][C:2]1[CH:3]=[C:4]([N:8]2[CH:12]=[N:11][N:10]=[N:9]2)[CH:5]=[CH:6][C:7]=1[N+:13]([O-:15])=[O:14]

Participants

3

Reactant 2

HCID 944Nitric AcidHCID 14450259HCID 14450259, compound

Product 1

HCID 14450250HCID 14450250, compound

Procedure

1-(3-Methylphenyl)tetrazole (11.3 g) was cautiously added at 0° to fuming nitric acid (100 cm3) with starting and the solution was then warmed on a steam bath for 5 minutes. The cooled solution was poured onto ice (200 g), and the solid material was filtered off, washed with water (100 cm3) and dried. Recrystallisation from ethyl acetate afforded 1-(3-methyl-4-nitrophenyl)tetrazole, m.p. 166°-168° (9.4 g).

Workup

  1. temperaturethe solution was then warmed on a steam bath for 5 minutes
  2. additionThe cooled solution was poured onto ice (200 g)
  3. filtrationthe solid material was filtered off
  4. washwashed with water (100 cm3)
  5. customdried
  6. customRecrystallisation from ethyl acetate

Sources & evidence

ORD record
ord-55b0fea9bb1d45e98cfc078ac967f7f8
Source dataset
uspto-grants-1989_06
Patent number
US04837334

Reaction notes

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