Pyridine → 6-Acetoxy-2H-pyran-3(6H)-one

HRID 1904387Notes

Reaction equation

[OH:1][CH:2]1[O:7][CH2:6][C:5](=[O:8])[CH:4]=[CH:3]1.N1C=CC=CC=1.[C:15](OC(=O)C)(=[O:17])[CH3:16]>>[C:15]([O:1][CH:2]1[O:7][CH2:6][C:5](=[O:8])[CH:4]=[CH:3]1)(=[O:17])[CH3:16]

Participants

Reactant 3

HCID 1049Pyridine

HCID 7918Acetic Anhydride

HCID 108554196-hydroxy-2H-pyran-3(6H)-one

Product 1

HCID 111162906-Acetoxy-2H-pyran-3(6H)-one

Conditions

Temperature: 0 °C

Procedure

24.0 g of 6-hydroxy-2H-pyran-3(6H)-one was dissolved in 80 ml of acetic anhydride. After cooling the solution to 0° C., 30 ml of pyridine was dropwise added thereto.

Sources & evidence

ORD record: ord-bc1bdb4c49cd4c108bab63973c83e9e3
Source dataset: uspto-grants-1989_06
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04837345

Reaction notes

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