Epichlorohydrin → 4-(oxiran-2-ylmethoxy)-1H-indole

HRID 1904397Notes

Reaction equation

HRID 1904397 reaction equation
[OH:1][C:2]1[CH:10]=[CH:9][CH:8]=[C:7]2[C:3]=1[CH:4]=[CH:5][NH:6]2.[CH2:11]([CH:13]1[O:15][CH2:14]1)Cl>>[O:15]1[CH:13]([CH2:11][O:1][C:2]2[CH:10]=[CH:9][CH:8]=[C:7]3[C:3]=2[CH:4]=[CH:5][NH:6]3)[CH2:14]1

Participants

3

Reactant 2

HCID 7835EpichlorohydrinHCID 754211H-indol-4-ol

Product 1

HCID 6050154-(oxiran-2-ylmethoxy)-1H-indole

Procedure

The title compound was synthesized from 4-hydroxyindole and epichlorohydrin by the method of Troxler et al. (Chem. Abs. 71, 70493c).

Sources & evidence

ORD record
ord-dd98a57b357b4817bc0994f1dce0a8d6
Source dataset
uspto-grants-1989_06
Patent number
US04837305

Reaction notes

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